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Measuring What Matters: Core Outcome Sets in Surgical Research and the GenderCOS Project

with Matteo Angelini | STEM Quest 3.0 | January 3, 2026

In this STEM Quest 3.0 session, Matteo Angelini introduces the concept of COS in surgical research and discusses their development, strengths, and limitations. The talk then focuses on the GenderCOS project, outlining how a core outcome set was developed for gender-affirming surgery and why standardization is particularly important in this field.

Special attention is given to patient-reported outcomes (PROs) as a central element of a COS, highlighting how patient perspectives on quality of life, function, and satisfaction can be systematically integrated into outcome frameworks without oversimplifying diverse experiences. The session provides a real-world look into how COS can shape patient-centred and meaningful evidence in healthcare globally.

Watch the full session, Measuring What Matters: Core Outcome Sets in Surgical Research and the GenderCOS Project, with Matteo and more STEM Quest 3.0 sessions here on Everything YSI!


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